Microreact demo
Microreact can be used to describe a large collection of 1451 isolates of Klebsiella pneumoniae, sampled from four countries (Colombia, India, Nigeria and The Philippines) between 2013 and 2019.
Klebsiella pneumoniae is a species of bacteria that is commonly found in natural and man-made environments. It has the impressive ability to colonise diverse animal species, including ourselves, pets and livestock. In healthy humans, K. pneumoniae is frequently found on the skin, in the mouth, and in the respiratory and gastrointestinal tracts. But K. pneumoniae is also an opportunistic pathogen, and can cause a wide range of infections in humans (and other animals). These include urinary tract, respiratory and bloodstream infections.
In recent years, there have been an increasing number of infections with K. pneumoniae that are resistant to antibiotics. One study found that carbapenem-resistant K. pneumoniae is the fastest-growing antibiotic resistance threat in Europe, with a 6-fold increase in the number of attributable deaths between 2007 and 2015. K. pneumoniae infections are particularly associated with patients who are very young (i.e. new-born babies), elderly, or immunocompromised.
Data taken from a series of articles published in 2021 in the journal Clinical Infectious Diseases:
Global collection article
Philippines article