FROM SWAB TO SERVER: TESTING, SEQUENCING AND SHARING DURING A PANDEMIC

@Pixabay

About the course

Sampling and testing are key to understanding where a disease is spreading. In the COVID-19 pandemic, the number of samples taken, analysed, tracked and shared have far surpassed any previous pandemic. This course follows the journey of a sample from the swab to the processed data used by experts in pandemic response. It discusses how to share data across teams and internationally, and the ethical and practical implications of using mass data on a pandemic scale.

Learning outcomes

  • Outline the journey from sample collection, through PCR to sequencing and data linkage
  • Compare the different sample types and how sampling strategy affects test performance
  • Explain the importance of linking genomic data to clinical and epidemiological data sets to address public health and scientific questions
  • Identify and explore ethical, legal and social implications of data use and sharing

Target audience

This course is for researchers, healthcare and public health professionals, diagnostic professionals, or any person involved in testing and analysis of disease samples.

Content

Week 1 - The journey of a sample

Week 2 - How to make data richer

Week 3 - A sample without data is nothing

Collaborators

Educators

Ana Filipe, MRC-University of Glasgow Centre for Virus Research, United Kingdom
Leigh Jackson, University of Exeter, United Kingdom
Moses Luutu Nsubuga, Makerere University, Uganda
Rogers Kamulegeya, Makerere University, Uganda

Contributors

Angela Beckett, University of Portsmouth, United Kingdom
Camila Romano, Universidade de São Paulo, Brazil
Collins Otieno, African Society for Laboratory Medicine, Ethiopia
Dodge Lim, Research Institute for Tropical Medicine, Philippines
Emma Thomson, MRC-University of Glasgow Centre for Virus Research, United Kingdom
Emmanuel Nasinghe, Makerere University, Uganda
Faith Nakazzi, Makerere University, Uganda
Gideon Nsubuga, Makerere University, Uganda
Hanna Pymont, United Kingdom Health Security Agency, United Kingdom
Harper VanSteenhouse, BioClavis Ltd, United States of America
Kirstyn Brunker, University of Glasgow, United Kingdom
Lei Lanna Dancel, Research Institute for Tropical Medicine, Philippines
Malebo Malope, Stellenbosch University, South Africa
Maria Magdalene Namaganda, Makerere University, Uganda
Ma. Ricci Gomez, Research Institute for Tropical Medicine, Philippines
Mark Webber, Quadram Institute, United Kingdom
Muhammad Yasir, Quadram Institute, United Kingdom
Nathan Moore, Hampshire Hospitals NHS Foundation Trust, United Kingdom
Newton Lwanga, Makerere University, Uganda
Paúl Cárdenas, Universidad San Francisco de Quito, Ecuador
Rodrigue Bikangui, Centre de Recherches Médicales de Lambaréné, Gabon
Sam Robson, University of Portsmouth, United Kingdom
Sarah Mwang, Africa CDC, Ethiopia
Senjuti Saha, Child Health Research Foundation, Bangladesh
Sharon Glaysher, University of Portsmouth, United Kingdom
Stephanie Hutchings, United Kingdom Health Security Agency, United Kingdom
Sunando Roy, University College of London, United Kingdom

Reviewers

Cassandra Soo, Wellcome Connecting Science, United Kingdom
Ricardo Khouri, Universidade Federal da Bahia and FIOCRUZ Bahia, Brazil

Education developer

Liã Bárbara Arruda, Wellcome Connecting Science, United Kingdom

COG-UK contributors

Sharon Peacock, University of Cambridge, United Kingdom
Alistair Darby, University of Liverpool, United Kingdom
Catherine Ludden, University of Cambridge, United Kingdom
Darren Smith, Northumbria University, United Kingdom
Ewan Harrison, Wellcome Sanger Institute, United Kingdom
Anna Markov, University of Cambridge, United Kingdom
Ellena Brooks, University of Cambridge, United Kingdom
Kim Smith, University of Cambridge, United Kingdom
Peter McEwan, University of Cambridge, United Kingdom

Wellcome Connecting Science contributors

Alice Matimba, Wellcome Connecting Science, United Kingdom
Dusanka Nikolic, Wellcome Connecting Science, United Kingdom
Jorge Batista da Rocha, Wellcome Connecting Science, United Kingdom
Mel Sharpe, Wellcome Connecting Science, United Kingdom
Rachel Berkson, Wellcome Connecting Science, United Kingdom
Treasa Creavin, Wellcome Connecting Science, United Kingdom

Original version

Original platform: FutureLearn
Original course page: Swab to server: testing, sequencing and sharing during a pandemic
Launch of the original version: 9 May 2022

Data collected on 31 May 2023
Number of joiners: 2,701
Number of countries reached: 139
Review score: 4.7/5 (49 reviews)


Any reuse of the course materials is encouraged with due acknowledgement.

License

Creative Commons Licence
This work is licensed under a Creative Commons Attribution 4.0 International License.

How to cite

COG-Train. (2022). From Swab to Server: Testing, Sequencing and Sharing during a Pandemic. Zenodo. https://doi.org/10.5281/zenodo.8164995


COG-Train
Wellcome 
Connecting Science